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Could A Drug For Eczema Be A Hair Loss Cure?

Category : Hair Loss Treatments 10/11/2018 7:04:30 PM

Doctors at the Massachusetts General Hospital (MGH) may have discovered a new hair loss "cure" while treating a teenage girl for severe eczema or atopic dermatitis, the doctors have reported hair growth as an unexpected side effect of the drug. In this article, we will go over the drug Dupixent (dupilumab) as a possible treatment for hair loss.

Dupixent (dupilumab) Hair Regrowth

In a case report published in the journal JAMA Dermatology, doctors discovered significant hair re-growth in a 13 year old patient that was suffering from alopecia totalis a severe form of alopecia areata, the patient had not grown any hair on the scalp since the age of two. The patient was also suffering from severe eczema (atopic dermatitis); a skin condition the patient suffered with since the age of one. As a result, doctors began treating the patient with Dupixent (dupilumab), an FDA approved treatment for moderate to severe eczema. After starting the treatment, the patient began to experience a significant amount of hair growth which left the doctors shocked and surprised.

Does this mean that Dupixent (dupilumab) is a hair loss cure?

Unfortunately, no it's not a cure however, it could be a treatment in the future once their have been clinical trials submitted to the FDA. In addition, there is only one report of hair re-growth associated with the medication Dupixent (dupilumab) which has been on the market for years. Furthermore, this medication can lead to undesirable side-effects which include oral herpes, conjunctivitis (pink eye) and upper respiratory infection.

Conclusion

While Dupixent (dupilumab) may have helped to treat alopecia totalis (an autoimmune condition) in one case, there isn't enough evidence to suggest that it can stop or even reverse the effects of androgenic alopecia (genetic hair loss). Furthermore, androgenic alopecia (genetic hair loss) is caused when the 5-alpha reductase enzyme converts testosterone in to dihydrotestosterone (DHT) through the blood stream, DHT is the hormone responsible for genetic hair loss. The mechanism that triggers genetic hair loss and alopecia totalis is completely different. Moreover, there is no scientific evidence that suggests this drug will reduce, inhibit or even block DHT from binding to the hair follicle receptor. Therefore, it is still recommended that hair loss sufferers use the only two FDA approved medications to treat genetic hair loss Propecia (finasteride) and Rogaine (minoxidil). While the case report published in the journal JAMA Dermatology sounds promising, it is too soon to know if this medication will work for genetic hair loss, but it may be worth using in conjunction with the aforementioned approved treatments in the future. 

Written and published by,

Melvin- Editorial Assistant and Forum Co-Moderator for the Hair Transplant Network, the Coalition Hair Loss Learning Center, and the Hair Loss Q&A Blog. Follow our Social Media Instagram @hairtransplantnetwork1 Facebook, Pintrest, Linkedin and YouTube.